The Karma research group at Karolinska Institutet is creating the world’s best-characterised breast cancer cohort. The aim is to reduce the mortality and incidence in breast cancer through translational research focusing on breast cancer screening and prevention.

READ MORE ABOUT THE KARMA STUDY

The Karma research group at Karolinska Institutet is creating the world’s best-characterised breast cancer cohort. The aim is to reduce the mortality and incidence in breast cancer through translational research focusing on breast cancer screening and prevention.

READ MORE ABOUT THE KARMA STUDY

Recent news

2021-03-19

KARISMA results: A nearly ten-fold descaling of tamoxifen have a potential treatment effect

The results from the 6-armed RCT trial KARISMA show that 2.5 mg of tamoxifen has the potential to be as effective in reducing incidence and recurrence of breast cancer as the established 20 mg dose.  Mammographic density change is a proxy for tamoxifen therapy response. We tested if lower doses of tamoxifen were non-inferior to...
2021-01-15

A thesis based on the Karma Cohort and focusing on breast cancer risk prediction and prevention was defended 15 January, 2021

The thesis included a paper describing a unique tool, STRATUS, for measuring mammographic density regardless of type of image and vendor. This tool and additional mammographic features was used for generating a risk prediction tool and described below, published 20-09-08 (please see below). The thesis also described the Karisma trial where lower doses of tamoxifen...
2020-12-12

A thesis based on the Karma Cohort and focusing on mammographic features was defended 11 December, 2020

Shadi Azam has published three papers (see links below) and have one paper in manuscript. Shadi has over the last years worked hard trying to understand the factors behind two mammographic “features” and how these features influence the risk of breast cancer. The features are mammographic density change and breast microcalcifications. None of them are currently particularly...
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Interview

Professor Per Hall talks about Karma