Genetic alterations that predispose women for later developing breast cancer are studied in collaboration with the Breast Cancer Association Consortium (BCAC), the University of Cambridge and the European Commission funded COGS project . The consortium includes more than 550 researchers at 300 research facilities across the globe.
Currently DNA from more that 20,000 Karma participants is genotyped together with over 275,000 non – Swedish samples. The samples are genotyped with a 570K single nucleotide polymorphism (SNP) markers custom array manufactured by Illumina, the so-called iCOGS OncoArray (https://epi.grants.cancer.gov/oncoarray/).
Professor Douglas Easton, head of BCAC – doug@srl.cam.ac.uk
A complete list of Breast Cancer Association Consortium publications with Karma samples can be found here.