Genetic alterations that predispose women for later developing breast cancer are studied in collaboration with the Breast Cancer Association Consortium (BCAC) (http://bcac.ccge.medschl.cam.ac.uk), the University of Cambridge and the European Commission funded COGS project (http://cogseu.org).The consortium includes more than 550 researchers at 300 research facilities across the globe.
Currently DNA from more that 20,000 Karma participants is genotyped together with over 275,000 non – Swedish samples. The samples are genotyped with a 570K single nucleotide polymorphism (SNP) markers custom array manufactured by Illumina, the so-called iCOGS OncoArray (https://epi.grants.cancer.gov/oncoarray/).
Professor Douglas Easton, head of BCAC – doug@srl.cam.ac.uk
A complete list of Breast Cancer Association Consortium publications with Karma samples can be found here.