News

2012-06-01

The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups

The elucidation of breast cancer subgroups and their molecular drivers requires integrated views of the genome and transcriptome from representative numbers of patients. We present an integrated analysis of copy number and gene expression in a discovery and validation set of 997 and 995 primary breast tumours, respectively, with long-term clinical follow-up. Inherited variants (copy…

2012-03-27

Dr Hall at Athena Breast Health Forum

Dr Hall is invited to San Francisco to participate in Athena Breast Health Forum.  A serie of discussions about outstanding questions and advancements in breast health between breast cancer experts, health care providers, patients and community members. Athena Breast Health Forum

2012-03-27

19p13.1 is a triple negative-specific breast cancer susceptibility locus

The 19p13.1 breast cancer susceptibility locus is a modifier of breast cancer risk in BRCA1 mutation carriers and is also associated with risk of ovarian cancer. Here we investigated 19p13.1 variation and risk of breast cancer subtypes, defined by estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor-2 (HER2) status, using 48,869…

2012-03-10

Karma has opened its 4th unit

Karma’s 4th sampling unit is situated in Lund. “Without Unilabs Skåne’s cooperation this had never been possible”, says Per Hall and continues “The Karma study is now recruiting almost a thousand women a week, which is a stunning figure”.

2012-01-27

Genome-wide association analysis identifies three new breast cancer susceptibility loci

Breast cancer is the most common cancer among women. To date, 22 common breast cancer susceptibility loci have been identified accounting for ∼8% of the heritability of the disease. We attempted to replicate 72 promising associations from two independent genome-wide association studies (GWAS) in ∼70,000 cases and ∼68,000 controls from 41 case-control studies and 9…

2011-12-20

New model for data export

We are proud to present the Karma Research Platform (beta) that we believe will become a game-changer for breast cancer prevention research.

2011-12-20

20 000 unique participants

The Karma study, which started in Helsingborg on January 11th 2011, has within eleven months recruited more than 20 000 participants

2011-12-20

Karma Research Platform (beta) up and running.

The Karma Research Platform (beta) is now up and running. As of today, any scientist with sound science can get access to the world’s best-characterized breast cancer cohort. “We are proud to present the Karma Research Platform. With more than 20,000 participants and a steady inflow of more than 800 women per week I believe…

2011-12-19

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